In Vivo Pharmacology Scientist (BBBH448778) Neuchâtel, Suisse
For our pharmaceutical client, localized in the French part of Switzerland, we are looking for a :
In vivo pharmacology Scientist
Your missions
- Lead the design and execution of in vivo studies to support the portfolio in immuno-oncology
- Drive innovation in animal experiments to leverage the best techniques for BEAT evaluation aligned with the 3Rs
- Collaborate with matrix functions to define in vivo and ex vivo study plans and endpoints to validate new targets
- Execute hands on in vivo work at all stages of animal experimentation including in life and ex vivo analysis
- Write technical protocols, prepare, and critically evaluate animal study plans and ethical approvals
- Communicate in a timely manner results to senior management
- Train and coach junior team members as needed
- Supervision of junior scientists and technicians as required
- Write technical reports, patents and manuscripts
- Lead external collaborations with CROs
- Presentation of results in English
- Perform data analysis on a regular basis and report data in laboratory notebooks in a timely manner
- Comply with all safety guidelines
Your profile
- Minimum of a PhD in the life sciences with at least 5 years’ experience working with immunology or oncology models in vivo, preferably in industry
- Experience with syngeneic or CDX models required
- Experience with humanized immune system (CD34 or PBMC) models highly desirable
- Strong experience with handling mice is required. LTK1 and LTK2 qualified candidates (or equivalent) preferred.
- Experience with handling rats is a plus
- Experience in cell culture including human and murine cells, in flow cytometry and in ELISA is required
- Experience in ImmunoHistoChemistry (IHC) is a plus
- Practical knowledge in data analysis using standard software is required
- Experience in drug discovery is required
- Prior management of small teams experience is preferred
- Comfortable working in an English speaking environment with fluency in French a plus
Your application
Please apply on-line. For more information, contact Ms Sophie Darthenay